Vitiligo causes white patches in your skin that could be unsightly and annoy. Vitiligo is a health condition caused by the loss of pigmentation in skin cells that can affect all races equally, but it can happen to anyone at any age. Vitiligo is not contagious, meaning you won’t catch it from somebody else if there are Vitiligo white patches on their skin. However, Vitiligo does tend to run in families, so if you have a parent or sibling who has Vitiligo, there’s a higher chance you will too.
Everyone’s Vitiligo causes are different, but Vitiligo tends to be associated with an autoimmune condition (the body attacks itself). Vitiligo affects the melanocytes in your skin cells. These cells are the ones that produce melanin, which is responsible for Vitiligo pigmentation in your skin. Vitiligo does not cause any permanent damage to your health, and there are Vitiligo treatments that can help you live with Vitiligo more comfortably.
There are no other Vitiligo symptoms beyond the Vitiligo white patches that appear on your skin. Vitiligo white patches can appear anywhere on your body. Vitiligo usually begins with one or two small Vitiligo white patches and then spreads over time.
Idiopathic guttate hypomelanosis (IGH):Â It is always asymmetrical Vitiligo in adults. Vitiligo spots appear as well defined, sharply circumscribed Vitiligo patches with round or oval shapes. White macules on the dorsal surface of hands and feet, often associated with Vitiligo of nails. It does not affect mucous membranes.
Nevus depigmentosus:Â These are Vitiligo-like macules. Vitiligo is present at birth or appears during the first few weeks of life. Vitiligo spots appear as well-defined Vitiligo patches with round or oval shapes.
Pityriasis alba: generally, occurs in children but may occur at any age. Vitiligo skin areas appear as ill-defined depigmented lesions without scale; sometimes, a hyperpigmented halo surrounds Vitiligo lesions.
Albinism:Â It also mimics vitiligo clinically. Albinism is a genetic disorder of pigmentation of the skin, hair, and eyes due to a defect in the tyrosinase enzyme (present in melanocytes). Albinos lack melanin in the skin, hair, and eyes. It is an autosomal recessive disorder occurring with equal frequency in males and females. At the same time, vitiligo is an acquired pigmentary disorder that causes loss of color (pigment) from portions of the skin resulting in irregular-shaped white patches or spots.
Piebaldism: It is a rare autosomal dominant disorder of pigmentation. A white forelock runs from the eyebrows, along the hairline to the back and sides of the head. The white patch may enlarge posteriorly to involve most of the scalp, including central baldness, producing a “skullcap†appearance. Other body hair and eyelashes are normal. Piebaldism results from an absence of melanocytes (pigment cells) in patches on the skin.
Tinea versicolor:Â It is due to an infestation of the superficial layers of the skin by a form of yeast usually present on the surface of the human body. It affects areas with more sebaceous glands (i.e., face, chest, and back). The antifungal drug fluconazole can treat this condition if it is severe or resistant to topical antifungals.
Progressive macular hypomelanosis is a rare acquired, localized form of hypopigmentation that begins in childhood and progresses slowly. Effects are usually light brown or tan macules with significant friction (from prolonged pressure).
Congenital diffuse hypomelanosis is an autosomal recessive disorder characterized by a nearly complete lack of cutaneous pigmentation at birth—diffuse areas of generalized hypotrichosis involving the trunk and extremities without hair follicles. The depigmented patches may enlarge over time; however, they do not undergo malignant transformation to melanoma.
Discoid Lupus:Â It is a chronic inflammatory skin disease common in women, particularly of African descent. It usually begins as a scaly red rash on the face and scalp, although any skin area can be affected. The areas most commonly affected are sun-exposed body areas such as the face, neck, ears, chest, upper back, and arms. These patches may be itchy and painful.
Morphea:Â It is a localized induration of the skin due to dermal fibrosis. The condition may be idiopathic or as part of an autoimmune disorder such as systemic lupus erythematosus, dermatomyositis, or morphea.
Tinea versicolor:Â It is due to an infestation of the superficial layers of the skin by a form of yeast usually present on the surface of the human body. It affects areas with more sebaceous glands (i.e., face, chest, and back). The antifungal drug fluconazole can treat this condition if it is severe or resistant to topical antifungals.
Sarcoidosis is a rare multisystem disorder when the body’s immune system makes an abnormal response to specific proteins called antigens. It can cause lesions like vitiligo on the skin, lungs, and other organs.
Leprosy:Â It is caused by the bacteria Mycobacterium lepre. Leprosy causes patchy loss in standard skin color and pigment-producing areas of flat whiteness thickened and dry appearance. Sometimes it may also cause missing or distorted eyebrows or eyelashes, eye inflammation, scarring and ulcers on the soles of the feet (also known as beriberi), slowed growth, and nerve damage.
Masked Melasma: Is caused by exposure to the sun. When dark-skinned people become very fair on some parts of their bodies, such as the forearm, they get a blotchy pigmentation called Morphea (localized induration of skin).
Post-inflammatory hyperpigmentation refers mainly to discoloration involving the face and is a common sequela of dermatitis, especially chronic irritant contact dermatitis.
A white patch on the skin may also be caused by other medical conditions affecting pigmentation. For example, seborrheic bleaching increases serine protease activity that causes melanocytes to lose their pigment.
This is a list of some other diseases and skin conditions that can cause Vitiligo or white patches on the skin:
1)Actinic keratoses,
2)Addison’s disease,
3)Amelanotic melanoma,
4)Anaemia, including iron deficiency anemia and hemolyticanemia,
5)Angiofibroma of tuberous sclerosis,
6)Bowenoid papulosis,
7)Chemical leukoderma; mercury toxicity [Occupational],
8)Chloroquine pigmentation (due to chloroquine therapy
9)Cicatricial pemphigoid,
10)Collie-Nair syndrome (localized dermal hypoplasia),
11)Cutaneous metastases from internal neoplasms,
12)Dimorphic fungi of the genera “Sporothrix” and “Phaeoacremonium.”
Usually, your skin doctor or dermatologist will diagnose vitiligo by looking at your skin.
Wood Lamp Test: Your skin doctor may also use a special ultraviolet light called a Woods Lamp. White patches on the skin will show up as lighter areas when compared with surrounding normal-colored skin. The presence of the pale regions – even if there are only small spots or freckles where pigment should generally be present – can indicate that vitiligo has begun. It is important to note that not everyone with vitiligo will show patchy areas of depigmentation when exposed to the Woods Lamp.
Skin Biopsy: In some instances, a skin biopsy may be used to make the diagnosis. A small piece of skin is removed and sent to the laboratory for examination by a pathologist – a doctor who specializes in tissue diseases. The pathologist will look at the sample of skin under a microscope. In some cases, this test is recommended to rule out other conditions such as leprosy or fungal infections that cause patches on the skin.
There is no permanent cure for vitiligo. However, various treatment options are available to restore a standard color (pigmentation) of the skin:
Skin Grafting: Skin grafting may be performed on more extensive vitiligo patches when repigmentation does not occur spontaneously or with topical treatments. Skin grafting works best for small patches with a moderate loss of pigment and would result in low-contrast, monochromatic skin color if depigmented. The skin graft is obtained from non-vitiligo areas of the body where there are no white patches.
Blister Grafting:Â Blister grafting is similar to skin grafting, but the blisters are made using a glass pipette or hypodermic needle heated over an alcohol flame. The blister fluid is then expressed, and the roof is peeled off to leave a thin split-thickness skin graft. These grafts are placed on areas of vitiligo after epithelializing with diluted triamcinolone acetonide ointment.
Isolated Cellular Grafts:Â Isolated cellular (non-meshed) grafts may be used as alternatives to skin grafting for small patches where the placement of a more extensive meshed skin autograft would result in a very poor cosmetic color.
The homeopathic treatment is more popular among the patients because it has no side effects and proved to be effective in many cases. You can visit Dr Batras clinic for vitiligo treatment. Treatments with ‘homeopathy’ include:
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